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The population impact of intervening on intermediates can be evaluated using observational data when certain conditions are met.

Evaluation is a systematic determination of a subject's merit, worth and significance, using criteria governed by a set of standards.

It can assist an organization, program, project or any other intervention or initiative to assess any aim, realisable concept/proposal, or any alternative, to help in decision-making; or to ascertain the degree of achievement or value in regard to the aim and objectives and results of any such action that has been completed.

Reducing human immunodeficiency virus (HIV) racial/ethnic disparities is a high priority.

Reductions in HIV racial/ethnic disparities can potentially be achieved by intervening on important intermediates.

So evaluation can be formative, that is taking place during the development of a concept or proposal, project or organization, with the intention of improving the value or effectiveness of the proposal, project, or organisation.

It can also be summative, drawing lessons from a completed action or project or an organisation at a later point in time or circumstance.We describe a useful conceptual and methodological framework for appropriately evaluating the impact of interventions to reduce HIV racial/ethnic disparities using observational data.This framework reframes relevant scientific questions in terms of a controlled direct effect and estimates a corresponding proportion eliminated.Evaluation is the structured interpretation and giving of meaning to predicted or actual impacts of proposals or results.It looks at original objectives, and at what is either predicted or what was accomplished and how it was accomplished.We review methods and conditions sufficient for accurate estimation within the proposed framework.

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